Acne Treatment with Isotretinoin (Accutane)

How Does Acne Develop?

Acne is the inflammation of the pilosebaceous unit—the part of your skin made up of the hair follicle and oil (sebaceous) gland. Its most common triggers include stress, hormonal changes, medications, poor hygiene, bad food choices and many others. When any of them is present, the following chain of events may occur:

Follicular Overgrowth

Factors that can cause cellular overgrowth inside the hair follicle include:

  • Hyperactivity of androgens or testosterone-like hormones
  • Reduced body levels of linoleic acid, a fatty acid that you can get only from the diet
  • Immunologic changes
  • The excess cells do not only grow fast, but they are also unusually sticky. The hair follicle has limited room, so cellular overgrowth can easily clog your pores and make them swell from debris and oil buildup.

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